HEREDITARY DIFFUSE GASTRIC CANCER
Hereditary Diffused Gastric Cancer or HDGC is believed to been around since the time of Napoleon Bonaparte.
The CDH1 gene was first found to be a hereditary risk factor for gastric cancer in 1998.
“The average age for someone with HDGC to be diagnosed with gastric cancer is 38; Women with HDGC also have an increased risk of lobular breast cancer.” – cancer.net
“HDGC is a genetic condition.This means that the cancer risk and other features of HDGC can be passed from generation to generation in a family.”
The gene associated with HDGC is CDH1. A mutation alternation; HDGC is becoming more common in younger patients.
E-cadherin protein (CDH-1) gene the risk of developing gastric cancer in a patient with CDH-1 gene is estimated at 67% for men and 83% for women before the age of 80.
“1-3% of all gastric cancers are of CDH-1 mutation
http://bestronghearted.org/cdh1-gene-mutation-how-is-it-inherited/